SCOOBY-DOO! FRANKENCREEPY tells of an evening when the Scooby-Doo gang were having dinner at a café, Felma, one of the group members search Scooby Doo ghosts, suddenly contacted by Cuthbert Crawley, a lawyer from the private family Felma. According to information from the lawyer, Felma must inherit from his uncle, a castle and and its contents that were in Transylvania.
After they came out of the café, how shocked they saw a ghost Baron (ancestor of Felma) blew up the car of mystery. Once the mystery car exploded a voice say if they had to stay away from Transylvania and if they keep coming to Transylvania, they would be cursed. However, unexpected fredd want to go to such places, because according Fredd to come to the area, they will find the person who should be responsible for the explosion of a mystery car.
After talks with all members of the gang, eventually all agreed to come to the venue, with the goal of finding who was responsible for the destruction of cars mystery and resolve the case of inheritance felma. Once they are through the long journey, finally reached the castle, they were greeted by Vanders, a caretaker of the castle. They were taken around the castle, and when entering the laboratory Baroon, velma hypnotized by a machine.