Hōzuki-san Chi no Aneki are brothers romantic comedy that follows the daily life of Goro Hōzuki, a high school kid with a sister named Haru who is not related to blood. Goro was embarrassed when selfish and lustful Haru plays pranks on him. Gorou Hazuki small crush on her sister Haru, but can not bring himself to admit it. However, Haru suspects, and use this knowledge to tease and humiliate him mercilessly. Surprisingly, this is not the beginning of the story hentai, but comedy with a slice-of-life elements.